Recent manuscripts
Archive
Editorial Board
Aims and Scope
Open Access
Indexing
Contact us
Authorship & COI
Principles of Transparency Checklist
Publication Ethics
Crossmark
Data Policies
Supporting Diversity
Instructions to authors (PDF)
Manuscript Types
Manuscript Formatting
How to submit
Special Publications & Reprints
Preprints
CONFERENCE PROCEEDING
Effect of smoking on salivary free amino acid levels
1
Department of Periodontology, Faculty of Dentistry, Ankara University, Ankara, Turkey
2
Department of Medical Biochemistry, School of Medicine, Acıbadem University, Ankara, Turkey
Publication date: 2018-10-03
Corresponding author
Cavid Mammadov
Department of Periodontology, Faculty of Dentistry, Ankara University, Ankara, Turkey
Department of Periodontology, Faculty of Dentistry, Ankara University, Ankara, Turkey
Tob. Induc. Dis. 2018;16(Suppl 3):A34
KEYWORDS
ABSTRACT
Objective:
The aim of this study was to identify probable intermediate biomarkers of disturbed pathways and their link between smoking.
Methods:
Un-stimulated whole saliva and serum samples were collected from a total of 30 systemically healthy participants with periodontally healthy smokers (S) (n=15) and non-smokers (n=15). Periodontal indices (plaque index, gingival index, probing depth, bleeding on probing, clinical attachment level) were recorded to confirm periodontal health. Saliva was purified, and a total of 28 amino acids and metabolites were analyzed by liquid chromatography-mass spectrometry (LC-MS/MS). Smoking status was validated measuring serum cotinine levels. Intergroup comparisons were assessed using the Mann Whitney U test.
Results:
When 28 amino acids were evaluated, smokers had statistically significantly higher cystathionine levels than non-smokers (p<0.05).
Conclusions:
Saliva cystathionine is associated with smoking in periodontally healthy individuals, and is possibly related to altered sulfuration pathway.
The aim of this study was to identify probable intermediate biomarkers of disturbed pathways and their link between smoking.
Methods:
Un-stimulated whole saliva and serum samples were collected from a total of 30 systemically healthy participants with periodontally healthy smokers (S) (n=15) and non-smokers (n=15). Periodontal indices (plaque index, gingival index, probing depth, bleeding on probing, clinical attachment level) were recorded to confirm periodontal health. Saliva was purified, and a total of 28 amino acids and metabolites were analyzed by liquid chromatography-mass spectrometry (LC-MS/MS). Smoking status was validated measuring serum cotinine levels. Intergroup comparisons were assessed using the Mann Whitney U test.
Results:
When 28 amino acids were evaluated, smokers had statistically significantly higher cystathionine levels than non-smokers (p<0.05).
Conclusions:
Saliva cystathionine is associated with smoking in periodontally healthy individuals, and is possibly related to altered sulfuration pathway.
Share
RELATED ARTICLE
| eISSN: | 1617-9625 |
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
