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RESEARCH PAPER
Smoking status in relation to serum folate and dietary vitamin intake
1
Department of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece
2
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
3
University Hospital of Crete, Heraklion, Greece
Submission date: 2008-06-16
Acceptance date: 2008-09-09
Publication date: 2008-09-09
Tobacco Induced Diseases 2008;4(September):8
KEYWORDS
ABSTRACT
Objective:
Cigarette smoke itself is an abundant source of free radicals and a major cause of oxidative stress, to which plasma antioxidants function as a vital protective and counterbalancing mechanism. The objective of this study was to investigate into the relationship between smoking status and serum and dietary micronutrient concentrations.
Design:
Cross-sectional study
Subjects – Setting:
502 farmers from the Valley of Messara in Crete were randomly selected and examined. Complete three-day and 24-hr recall questionnaires were collected along with anthropometrical, physical activity and clinical data from all participating subjects.
Results:
After adjusting for age, gender and number of fasting days adhered to per year, current smokers were found to have a lower dietary intake of vitamin C (112.1 mg vs. 136.4 mg, p = 0.03), fibre (16.6 g vs. 19.1 g, p = 0.006) and fruits and vegetables (339 g vs. 412 g, p = 0.014), while dietary vitamin B1 intake was found to be higher (1.7 mg vs. 1.4 mg, p = 0.02) in comparison to non/ex smokers. Dietary intake of meat, folate and vitami A, E, B2, B6 and B12 did not differ between the groups. Controlling age, gender, fasting days and dietary micronutrient intake, serum folate levels were found to be lower among smokers (geometric mean 15.3 nmol/L vs. 17.7 nmol/L, p = 0.023), while serum iron and vitamin B12 levels were not affected by smoking status.
Conclusion:
Current smoking status affects dietary nutrient intake as well as plasma folate levels. The above coherence between antioxidant depletion and reduced antioxidant intake may predispose smokers to the premature development of tobacco related mortality and morbidity.
Cigarette smoke itself is an abundant source of free radicals and a major cause of oxidative stress, to which plasma antioxidants function as a vital protective and counterbalancing mechanism. The objective of this study was to investigate into the relationship between smoking status and serum and dietary micronutrient concentrations.
Design:
Cross-sectional study
Subjects – Setting:
502 farmers from the Valley of Messara in Crete were randomly selected and examined. Complete three-day and 24-hr recall questionnaires were collected along with anthropometrical, physical activity and clinical data from all participating subjects.
Results:
After adjusting for age, gender and number of fasting days adhered to per year, current smokers were found to have a lower dietary intake of vitamin C (112.1 mg vs. 136.4 mg, p = 0.03), fibre (16.6 g vs. 19.1 g, p = 0.006) and fruits and vegetables (339 g vs. 412 g, p = 0.014), while dietary vitamin B1 intake was found to be higher (1.7 mg vs. 1.4 mg, p = 0.02) in comparison to non/ex smokers. Dietary intake of meat, folate and vitami A, E, B2, B6 and B12 did not differ between the groups. Controlling age, gender, fasting days and dietary micronutrient intake, serum folate levels were found to be lower among smokers (geometric mean 15.3 nmol/L vs. 17.7 nmol/L, p = 0.023), while serum iron and vitamin B12 levels were not affected by smoking status.
Conclusion:
Current smoking status affects dietary nutrient intake as well as plasma folate levels. The above coherence between antioxidant depletion and reduced antioxidant intake may predispose smokers to the premature development of tobacco related mortality and morbidity.
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International Urology and Nephrology
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Toxic elements in packed red blood cells from smoker donors: a risk for paediatric transfusion?
Renata Boehm, Carolina Cohen, Rianne Pulcinelli, Greice Caletti, Almeri Balsan, Sabrina Nascimento, Rafael Rocha, Enrique Calderon, Tatiana Saint’Pierre, Solange Garcia, Leo Sekine, Tor Onsten, Adriana Gioda, Rosane Gomez
Vox Sanguinis
Renata Boehm, Carolina Cohen, Rianne Pulcinelli, Greice Caletti, Almeri Balsan, Sabrina Nascimento, Rafael Rocha, Enrique Calderon, Tatiana Saint’Pierre, Solange Garcia, Leo Sekine, Tor Onsten, Adriana Gioda, Rosane Gomez
Vox Sanguinis
30.
High Serum Folate Concentration Is Associated with Better Lung Function in Male Chronic Obstructive Pulmonary Disease Patients Who Are Current Smokers: Analysis of Nationwide Population-Based Survey
Taeyun Kim, Chul-Ho Oak, Mann-Hong Jung, Tae-Won Jang, Jehun Kim
Nutrients
Taeyun Kim, Chul-Ho Oak, Mann-Hong Jung, Tae-Won Jang, Jehun Kim
Nutrients
31.
Novel predictive risk factor for Erectile Dysfunction: Serum folic acid
Abhimanyu Gupta, Shivam Priyadarshi, Nachiket Vyas, Govind Sharma, Prafulla Swain
Andrologia
Abhimanyu Gupta, Shivam Priyadarshi, Nachiket Vyas, Govind Sharma, Prafulla Swain
Andrologia
32.
Dietary Intake of Folate and Assessment of the Folate Deficiency Prevalence in Slovenia Using Serum Biomarkers
Igor Pravst, Živa Lavriša, Maša Hribar, Hristo Hristov, Naska Kvarantan, Barbara Seljak, Matej Gregorič, Urška Blaznik, Nadan Gregorič, Katja Zaletel, Adrijana Oblak, Joško Osredkar, Katja Žmitek, Anita Kušar
Nutrients
Igor Pravst, Živa Lavriša, Maša Hribar, Hristo Hristov, Naska Kvarantan, Barbara Seljak, Matej Gregorič, Urška Blaznik, Nadan Gregorič, Katja Zaletel, Adrijana Oblak, Joško Osredkar, Katja Žmitek, Anita Kušar
Nutrients
33.
Plasma Cotinine Is Positively Associated with Homocysteine in Smokers but Not in Users of Smokeless Tobacco
Elisabet Söderström, Torbjörn Nilsson, Jörn Schneede, Per-Magne Ueland, Øivind Midttun, Björn Gylling, Ingegerd Johansson, Johan Hultdin
International Journal of Environmental Research and Public Health
Elisabet Söderström, Torbjörn Nilsson, Jörn Schneede, Per-Magne Ueland, Øivind Midttun, Björn Gylling, Ingegerd Johansson, Johan Hultdin
International Journal of Environmental Research and Public Health
34.
A Retrospective Cross-Sectional Cohort Trial Assessing the Prevalence of MTHFR Polymorphisms and the Influence of Diet on Platinum Resistance in Ovarian Cancer Patients
Caitlin Phillips-Chavez, Jermaine Coward, Michael Watson, Janet Schloss
Cancers
Caitlin Phillips-Chavez, Jermaine Coward, Michael Watson, Janet Schloss
Cancers
35.
Interaction between serum vitamin C levels and smoking on the periodontal condition in older adults
Akihiro Yoshihara, Keisuke Nakashima, Kana Suwama, Ayuko Odajima, Takayuki Yamaga, Hiroshi Ogawa
Journal of Periodontal Research
Akihiro Yoshihara, Keisuke Nakashima, Kana Suwama, Ayuko Odajima, Takayuki Yamaga, Hiroshi Ogawa
Journal of Periodontal Research
36.
Epigenetic Determinants of Racial Disparity in Breast Cancer: Looking beyond Genetic Alterations
Shriya Joshi, Chakravarthy Garlapati, Ritu Aneja
Cancers
Shriya Joshi, Chakravarthy Garlapati, Ritu Aneja
Cancers
37.
Folate and vitamin B12 status: temporal evaluation after mandatory fortification in Brazil
Cecília Palchetti, Josiane Steluti, Cristiane Sales, Regina Fisberg, Dirce Marchioni
European Journal of Clinical Nutrition
Cecília Palchetti, Josiane Steluti, Cristiane Sales, Regina Fisberg, Dirce Marchioni
European Journal of Clinical Nutrition
38.
Association Between Serum Folate and Lung Function in People with and without Chronic Obstructive Pulmonary Disease: Results from NHANES 2007–2012.
Xiang wen, Huajing Yang, Luyao Wang
Xiang wen, Huajing Yang, Luyao Wang
39.
The dietary inflammatory index and new-onset hypertension in Chinese adults: a nationwide cohort study
Ze Xu, Xue Li, Li Ding, Zhaofeng Zhang, Yongye Sun
Food & Function
Ze Xu, Xue Li, Li Ding, Zhaofeng Zhang, Yongye Sun
Food & Function
40.
Folate Biomarkers, Folate Intake, and Risk of Death From All Causes, Cardiovascular Disease, and Cancer: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies
Melika Fallah, Maryam Karim Dehnavi, Keyhan Lotfi, Azadeh Aminianfar, Leila Azadbakht, Ahmad Esmaillzadeh
Nutrition Reviews
Melika Fallah, Maryam Karim Dehnavi, Keyhan Lotfi, Azadeh Aminianfar, Leila Azadbakht, Ahmad Esmaillzadeh
Nutrition Reviews
| eISSN: | 1617-9625 |
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