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RESEARCH PAPER
Smoking status in relation to serum folate and dietary vitamin intake
1
Department of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece
2
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
3
University Hospital of Crete, Heraklion, Greece
Submission date: 2008-06-16
Acceptance date: 2008-09-09
Publication date: 2008-09-09
Tobacco Induced Diseases 2008;4(September):8
KEYWORDS
ABSTRACT
Objective:
Cigarette smoke itself is an abundant source of free radicals and a major cause of oxidative stress, to which plasma antioxidants function as a vital protective and counterbalancing mechanism. The objective of this study was to investigate into the relationship between smoking status and serum and dietary micronutrient concentrations.
Design:
Cross-sectional study
Subjects – Setting:
502 farmers from the Valley of Messara in Crete were randomly selected and examined. Complete three-day and 24-hr recall questionnaires were collected along with anthropometrical, physical activity and clinical data from all participating subjects.
Results:
After adjusting for age, gender and number of fasting days adhered to per year, current smokers were found to have a lower dietary intake of vitamin C (112.1 mg vs. 136.4 mg, p = 0.03), fibre (16.6 g vs. 19.1 g, p = 0.006) and fruits and vegetables (339 g vs. 412 g, p = 0.014), while dietary vitamin B1 intake was found to be higher (1.7 mg vs. 1.4 mg, p = 0.02) in comparison to non/ex smokers. Dietary intake of meat, folate and vitami A, E, B2, B6 and B12 did not differ between the groups. Controlling age, gender, fasting days and dietary micronutrient intake, serum folate levels were found to be lower among smokers (geometric mean 15.3 nmol/L vs. 17.7 nmol/L, p = 0.023), while serum iron and vitamin B12 levels were not affected by smoking status.
Conclusion:
Current smoking status affects dietary nutrient intake as well as plasma folate levels. The above coherence between antioxidant depletion and reduced antioxidant intake may predispose smokers to the premature development of tobacco related mortality and morbidity.
Cigarette smoke itself is an abundant source of free radicals and a major cause of oxidative stress, to which plasma antioxidants function as a vital protective and counterbalancing mechanism. The objective of this study was to investigate into the relationship between smoking status and serum and dietary micronutrient concentrations.
Design:
Cross-sectional study
Subjects – Setting:
502 farmers from the Valley of Messara in Crete were randomly selected and examined. Complete three-day and 24-hr recall questionnaires were collected along with anthropometrical, physical activity and clinical data from all participating subjects.
Results:
After adjusting for age, gender and number of fasting days adhered to per year, current smokers were found to have a lower dietary intake of vitamin C (112.1 mg vs. 136.4 mg, p = 0.03), fibre (16.6 g vs. 19.1 g, p = 0.006) and fruits and vegetables (339 g vs. 412 g, p = 0.014), while dietary vitamin B1 intake was found to be higher (1.7 mg vs. 1.4 mg, p = 0.02) in comparison to non/ex smokers. Dietary intake of meat, folate and vitami A, E, B2, B6 and B12 did not differ between the groups. Controlling age, gender, fasting days and dietary micronutrient intake, serum folate levels were found to be lower among smokers (geometric mean 15.3 nmol/L vs. 17.7 nmol/L, p = 0.023), while serum iron and vitamin B12 levels were not affected by smoking status.
Conclusion:
Current smoking status affects dietary nutrient intake as well as plasma folate levels. The above coherence between antioxidant depletion and reduced antioxidant intake may predispose smokers to the premature development of tobacco related mortality and morbidity.
REFERENCES (34)
1.
Ezzati M, Lopez : Estimates of global mortality attributable to smoking in 2000. The Lancet. 2003, 362: 847-52.
2.
International Agency for Research on Cancer. IARC: Monographs on the Evaluation of the carcinogenic risks to humans: Tobacco smoking. 1986, Lyon (France). International Agency for Research on Cancer, 38.
3.
Burke A, FitzGerald G: Oxidative stress and smoking-induced vascular injury. Progress In Cardiovascular Diseases. 2003, 46 (1): 79-90.
4.
Pryor , Stone : Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate and peroxynitrite. Annals of the New York Academy of Sciences. 1993, 686: 12-27.
5.
Thurnham DI, Northrop-Clewes CA: Effects of infection on nutritional and immune status. Diet and human immune function. Edited by: Hughes DA, Darlington LG, Bendich A. 2004, New Jersey: Humana Press, 35-63.
6.
Alberg A: The influence of cigarette smoking on circulating concentrations of antioxidant micronutrients. Toxicology. 2002, 180: 121-137.
7.
Zondervan KT, Ocke MC, Smit HA, Seidell JC: Do dietary and supplementary intakes of antioxidants differ with smoking status?. International Journal of Epidemiology. 1996, 25: 70-79.
8.
Margetts BM, Jackson AA: The determinants of plasma b-carotene: interaction between smoking and other lifestyle factors. European Journal of Clinical Nutrition. 1996, 50: 236-238.
9.
Touvier M, Niravong M, Volatier JL, Lafay L, Lioret S, Clavel-Chapelon F, Boutron-Ruault MC: Dietary patterns associated with vitamin/mineral supplement use and smoking among women of the E3N-EPIC cohort. Eur J Clin Nutr. 2007.
10.
Padrao P, Lunet N, Santos AC, Barros H: Smoking, alcohol, and dietary choices: evidence from the Portuguese National Health Survey. BMC Public Health. 2007, 7: 138.
11.
Kafatos AG, Verhagen H, Moschandreas J, Apostolaki I, Van Westerop J: Mediterranean diet of Crete: foods and nutrient content. Journal of the American Dietetic Association. 2000, 100: 1487-1493.
12.
Food and Nutrition Board IoM: Dietary reference intakes for thiamin, riboflavin, niacin, vitamin b6, folate, vitamin b12, pantothenic acid, biotin, and choline. A report of the standing committee on the scientific evaluation of dietary reference intakes and its panel on folate, other B vitamins, and choline and subcommittee on upper reference levels of nutrients. 1998, Washington DC: National Academic Press.
13.
Sarri K, Linardakis M, Codrington C, Kafatos A: Does the periodic vegetarianism of Greek Orthodox Christians benefit blood pressure?. Preventive Medicine. 2007, 44 (4): 341-8.
14.
Sarri KO, Linardakis MK, Bervanaki FN, Tzanakis NE, Kafatos AG: Greek Orthodox fasting rituals: a hidden characteristic of the Mediterranean diet of Crete. British Journal of Nutrition. 2004, 92 (2): 277-84.
15.
Pitsavos C, Panagiotakos D, Chrysohoou C, Stefanadis C: Epidemiology of cardiovascular risk factors in Greece: aims, design and baseline characteristics of the ATTICA study. BMC Public Health. 2003, 3 (1): 32.
16.
Huisman M, Kunst AE, Mackenbach JP: Inequalities in the prevalence of smoking in the European Union: comparing education and income. Preventive Medicine. 2005, 40: 756-764.
17.
Refsum H, Ueland PM, Nygard O, Vollset SE: Homocysteine and cardiovascular disease. Annual Review of Medicine. 1998, 49: 31-62.
18.
Northrop-Clewes CA, Thurnham DI: Monitoring micronutrients in cigarette smokers. Clinica Chima Acta. 2000, 377: 14-38.
19.
Ortega RM, Lopez-Sobaler AM, Gonzalez-Gross MM, Redondo RM, Marzana I, Zamora MJ, Andres P: Influence of smoking on folate intake and blood folate concentrations in a group of elderly Spanish men. Journal of the American College of Nutrition. 1994, 13: 68-72.
20.
Piyathilake CJ, Macaluso M, Hine RJ, Richards EW, Krumdieck CL: Local and systemic effects of cigarette smoking on folate and vitamin B-12. American Journal of Clinical Nutrition. 1994, 60: 559-66.
21.
Pagan K, Hou J, Goldenberg RL, Cliver SP, Tamura T: Effect of smoking on serum concentrations of total homocysteine and B vitamins in midpregnancy. Clin Chim Acta. 2001, 306: 103-9.
22.
Relton CL, Pearce MS, Parker L: The influence of erythrocyte folate and serum vitamin B12 status on birth weight. British Journal of Nutrition. 2005, 93: 593-9.
23.
Tungtrongchitr R, Pongpaew P, Soonthornruengyot M, Viroonudomphol D, Vudhivai N, Tungtrongchitr A, Phonrat B, Pooudong S, Schelp FP: Relationship of tobacco smoking with serum vitamin B12, folic acid and haematological indices in healthy adults. Public Health Nutrition. 2003, 6: 675-81.
24.
Kim S, Kim J, Shin H, Keen C: Influence of smoking on markers of oxidative stress and serum mineral concentrations in teenage girls in Korea. Nutrition. 2003, 19: 240-243.
25.
Milman M, Kirchhoff M: Relationship between serum ferritin and risk factors for ischaemic heart disease in 2235 Danes aged 30–60 years. Journal of Internal Medicine. 1999, 245: 423-433.
26.
Hughes K, Choo M, Kuperan P, Ong CN, Aw TC: Cardiovascular risk factors in relation to cigarette smoking: a population-based survey among Asians in Singapore. Atherosclerosis. 1998, 137: 253-258.
27.
Vardavas CI, Majchrzak D, Wagner K-H, Elmadfa I, Kafatos A: The antioxidant and phylloquinone content of wildly grown greens in Crete. Food Chemistry. 2006, 99 (4): 813-821.
28.
Zeghini S, Kallithraka S, Simopoulos A, Kypryotakis Z: Nutritional composition of selected wild plants in the diet of Crete. World review of nutrition and dietetics. 2003, 91: 22-40.
29.
Dyer AR, Elliot P, Stamler J, Chan Q, Ueshima H, Zhou BF: Dietary intake in male and female smokers, ex-smokers and never smokers: the INTERMAP study. Journal of Human Hypertension. 2003, 17: 641-54.
30.
Ortega RM, Requejo AM, Lopez-Sobaler AM, Navia B, Mena MC, Basabe B, Andres P: Smoking and passive smoking as conditioners of folate in young women. Journal of the American College of Nutrition. 2004, 23: 365-71.
31.
Ma J, Hampl J, Betts N: Antioxidant intake and smoking status: data from the continuing survey of foods intakes by individuals 1994–1996. American Journal of Clinical Nutrition. 2000, 71: 774-80.
32.
Nomura AM, Hankin JH, Henderson BE, Wilkens LR, Murphy SP, Pike MC, Le Marchand L, Stram DO, Monroe KR, Kolonel LN: Dietary fiber and colorectal cancer risk: the multiethnic cohort study. Cancer Causes and Control. 2007, 18 (7): 753-64.
33.
Donaldson MS: Nutrition and cancer: a review of the evidence for an anti-cancer diet. Nutrition Journal. 2004, 3: 19.
34.
Divisi D, Di Tommaso S, Salvemini S, Garramone M, Crisci R: Diet and cancer. Acta Biomedica. 2006, 77 (2): 118-23.
CITATIONS (40):
1.
Lifestyle and genetic determinants of folate and vitamin B12 levels in a general adult population
Betina H. Thuesen, Lise Lotte N. Husemoen, Lars Ovesen, Torben Jørgensen, Mogens Fenger, Allan Linneberg
British Journal of Nutrition
Betina H. Thuesen, Lise Lotte N. Husemoen, Lars Ovesen, Torben Jørgensen, Mogens Fenger, Allan Linneberg
British Journal of Nutrition
2.
Cardiovascular disease risk factors and dietary habits of farmers from Crete 45 years after the first description of the Mediterranean diet
Constantine I. Vardavas, Manolis K. Linardakis, Christos M. Hatzis, Wim H.M. Saris, Anthony G. Kafatos
European Journal of Cardiovascular Prevention & Rehabilitation
Constantine I. Vardavas, Manolis K. Linardakis, Christos M. Hatzis, Wim H.M. Saris, Anthony G. Kafatos
European Journal of Cardiovascular Prevention & Rehabilitation
3.
Diet, life-style and cardiovascular morbidity in the rural, free living population of Elafonisos island
Chris J. Kapelios, Ioannis Kyriazis, Ioannis Ioannidis, Charilaos Dimosthenopoulos, Erifili Hatziagelaki, Stavros Liatis
BMC Public Health
Chris J. Kapelios, Ioannis Kyriazis, Ioannis Ioannidis, Charilaos Dimosthenopoulos, Erifili Hatziagelaki, Stavros Liatis
BMC Public Health
4.
Exposure to solar ultraviolet radiation is associated with a decreased folate status in women of childbearing age
D. Borradale, E. Isenring, E. Hacker, M.G. Kimlin
Journal of Photochemistry and Photobiology B: Biology
D. Borradale, E. Isenring, E. Hacker, M.G. Kimlin
Journal of Photochemistry and Photobiology B: Biology
5.
Determinants of folate and vitamin B12 plasma levels in the French E3N-EPIC cohort
Jordi de Batlle, Marco Matejcic, Veronique Chajes, Hortensia Moreno-Macias, Amina Amadou, Nadia Slimani, David G. Cox, Françoise Clavel-Chapelon, Guy Fagherazzi, Isabelle Romieu
European Journal of Nutrition
Jordi de Batlle, Marco Matejcic, Veronique Chajes, Hortensia Moreno-Macias, Amina Amadou, Nadia Slimani, David G. Cox, Françoise Clavel-Chapelon, Guy Fagherazzi, Isabelle Romieu
European Journal of Nutrition
7.
Effect of cigarette smoking on plasma homocysteine concentrations
Dhouha Haj Mouhamed, Asma Ezzaher, Fadoua Neffati, Wahiba Douki, Mohamed Fadhel Najjar
Clinical Chemistry and Laboratory Medicine
Dhouha Haj Mouhamed, Asma Ezzaher, Fadoua Neffati, Wahiba Douki, Mohamed Fadhel Najjar
Clinical Chemistry and Laboratory Medicine
8.
Predictors of folate status among pregnant Japanese women: the Hokkaido Study on Environment and Children’s Health, 2002–2012
Thamar A. Yila, Atsuko Araki, Seiko Sasaki, Chihiro Miyashita, Kumiko Itoh, Tamiko Ikeno, Eiji Yoshioka, Sumitaka Kobayashi, Houman Goudarzi, Toshiaki Baba, Titilola Braimoh, Hisanori Minakami, Toshiaki Endo, Kazuo Sengoku, Reiko Kishi
British Journal of Nutrition
Thamar A. Yila, Atsuko Araki, Seiko Sasaki, Chihiro Miyashita, Kumiko Itoh, Tamiko Ikeno, Eiji Yoshioka, Sumitaka Kobayashi, Houman Goudarzi, Toshiaki Baba, Titilola Braimoh, Hisanori Minakami, Toshiaki Endo, Kazuo Sengoku, Reiko Kishi
British Journal of Nutrition
9.
Folate intake and folate serum levels in men and women from two European populations: The IMMIDIET project
George Pounis, Augusto F. Di Castelnuovo, Michel de Lorgeril, Vittorio Krogh, Alfonso Siani, Jozef Arnout, Francesco P. Cappuccio, Martien van Dongen, Bruno Zappacosta, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello
Nutrition
George Pounis, Augusto F. Di Castelnuovo, Michel de Lorgeril, Vittorio Krogh, Alfonso Siani, Jozef Arnout, Francesco P. Cappuccio, Martien van Dongen, Bruno Zappacosta, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello
Nutrition
10.
Partner cigarette smoking and risk of neural tube defects among infants of non-smoking women in northern China
Zhiwen Li, Le Zhang, Rongwei Ye, Jianmeng Liu, Lijun Pei, Xiaoying Zheng, Aiguo Ren
Tobacco Control
Zhiwen Li, Le Zhang, Rongwei Ye, Jianmeng Liu, Lijun Pei, Xiaoying Zheng, Aiguo Ren
Tobacco Control
11.
Smoking and dietary inadequacy among Inuvialuit women of child bearing age in the Northwest Territories, Canada
Fariba Kolahdooz, Nonsikelelo Mathe, Lalage A Katunga, Lindsay Beck, Tony Sheehy, Andre Corriveau, Sangita Sharma
Nutrition Journal
Fariba Kolahdooz, Nonsikelelo Mathe, Lalage A Katunga, Lindsay Beck, Tony Sheehy, Andre Corriveau, Sangita Sharma
Nutrition Journal
12.
A single blueberry (Vaccinium corymbosum) portion does not affect markers of antioxidant defence and oxidative stress in healthy volunteers following cigarette smoking
Cristian Del Bo’, Marisa Porrini, Jonica Campolo, Marina Parolini, Claudia Lanti, Dorothy Klimis-Zacas, Patrizia Riso
Mutagenesis
Cristian Del Bo’, Marisa Porrini, Jonica Campolo, Marina Parolini, Claudia Lanti, Dorothy Klimis-Zacas, Patrizia Riso
Mutagenesis
13.
Paraoxonase 1 R/Q alleles are associated with differential accumulation of saturated versus 20:5n3 fatty acid in human adipose tissue
Alexandros Zafiropoulos, Manolis Linardakis, Eugene H. J. M. Jansen, Aristidis M. Tsatsakis, Antonis Kafatos, George N. Tzanakakis
Journal of Lipid Research
Alexandros Zafiropoulos, Manolis Linardakis, Eugene H. J. M. Jansen, Aristidis M. Tsatsakis, Antonis Kafatos, George N. Tzanakakis
Journal of Lipid Research
14.
Mechanisms of action for arsenic in cardiovascular toxicity and implications for risk assessment
Mandeep S. Sidhu, Karan P. Desai, Heather N. Lynch, Lorenz R. Rhomberg, Barbara D. Beck, Ferdinand J. Venditti
Toxicology
Mandeep S. Sidhu, Karan P. Desai, Heather N. Lynch, Lorenz R. Rhomberg, Barbara D. Beck, Ferdinand J. Venditti
Toxicology
15.
Association between biomarker-quantified antioxidant status during pregnancy and infancy and allergic disease during early childhood: A systematic review
Evridiki Patelarou, Gianna Giourgouli, Aikaterini Lykeridou, Evagelia Vrioni, Nikolaos Fotos, Eleni Siamaga, Victoria Vivilaki, Hero Brokalaki
Nutrition Reviews
Evridiki Patelarou, Gianna Giourgouli, Aikaterini Lykeridou, Evagelia Vrioni, Nikolaos Fotos, Eleni Siamaga, Victoria Vivilaki, Hero Brokalaki
Nutrition Reviews
16.
Prevalence of obesity and physical inactivity among farmers from Crete (Greece), four decades after the seven countries study
C.I. Vardavas, M.K. Linardakis, C.M. Hatzis, W.H.M. Saris, A.G. Kafatos
Nutrition, Metabolism and Cardiovascular Diseases
C.I. Vardavas, M.K. Linardakis, C.M. Hatzis, W.H.M. Saris, A.G. Kafatos
Nutrition, Metabolism and Cardiovascular Diseases
18.
Obesity Is Associated with Increased Red Blood Cell Folate Despite Lower Dietary Intakes and Serum Concentrations
Julia K Bird, Alayne G Ronnenberg, Sang-Woon Choi, Fangling Du, Joel B Mason, Zhenhua Liu
The Journal of Nutrition
Julia K Bird, Alayne G Ronnenberg, Sang-Woon Choi, Fangling Du, Joel B Mason, Zhenhua Liu
The Journal of Nutrition
19.
Review of biomarkers to assess the effects of switching from cigarettes to modified risk tobacco products
Michael John Peck, Edward B. Sanders, Gerhard Scherer, Frank Lüdicke, Rolf Weitkunat
Biomarkers
Michael John Peck, Edward B. Sanders, Gerhard Scherer, Frank Lüdicke, Rolf Weitkunat
Biomarkers
20.
Estimation of Serum and Erythrocyte Folate Concentrations in the New Zealand Adult Population within a Background of Voluntary Folic Acid Fortification
Kathryn E. Bradbury, Sheila M. Williams, Jim I. Mann, Rachel C. Brown, Winsome Parnell, C. Murray Skeaff
The Journal of Nutrition
Kathryn E. Bradbury, Sheila M. Williams, Jim I. Mann, Rachel C. Brown, Winsome Parnell, C. Murray Skeaff
The Journal of Nutrition
21.
Folate intake in a Swedish adult population: Food sources and predictive factors
Celia Monteagudo, Henrik Scander, Bente Nilsen, Agneta Yngve
Food & Nutrition Research
Celia Monteagudo, Henrik Scander, Bente Nilsen, Agneta Yngve
Food & Nutrition Research
22.
Does adherence to the Mediterranean diet have a protective effect against active and passive smoking?
C.I. Vardavas, A.D. Flouris, A. Tsatsakis, A.G. Kafatos, W.H.M. Saris
Public Health
C.I. Vardavas, A.D. Flouris, A. Tsatsakis, A.G. Kafatos, W.H.M. Saris
Public Health
23.
Healthcare-related characteristics of low vs normal folate levels among women of child-bearing age
Vijay N. Joish, Grace Lin, Richard Lynen
Journal of Medical Economics
Vijay N. Joish, Grace Lin, Richard Lynen
Journal of Medical Economics
25.
Analysis of Short-Term Smoking Effects in PBMC of Healthy Subjects—Preliminary Study
Joanna Wieczfinska, Tomasz Kowalczyk, Przemyslaw Sitarek, Ewa Skała, Rafal Pawliczak
International Journal of Environmental Research and Public Health
Joanna Wieczfinska, Tomasz Kowalczyk, Przemyslaw Sitarek, Ewa Skała, Rafal Pawliczak
International Journal of Environmental Research and Public Health
26.
The Relevance of Vitamin and Iron Deficiency in Patients with Inflammatory Bowel Diseases in Patients of the Swiss IBD Cohort
Matiar Madanchi, Stefania Fagagnini, Nicolas Fournier, Luc Biedermann, Jonas Zeitz, Edouard Battegay, Lukas Zimmerli, Stephan R Vavricka, Gerhard Rogler, Michael Scharl, Claudia Anderegg, Peter Bauerfeind, Christoph Beglinger, Stefan Begré, Dominique Belli, José M Bengoa, Luc Biedermann, Beat Bigler, Janek Binek, Mirjam Blattmann, Stephan Boehm, Jan Borovicka, Christian P Braegger, Nora Brunner, Patrick Bühr, Bernard Burnand, Emanuel Burri, Sophie Buyse, Matthias Cremer, Dominique H Criblez, Philippe de Saussure, Lukas Degen, Joakim Delarive, Christopher Doerig, Barbara Dora, Gian Dorta, Mara Egger, Tobias Ehmann, Ali El-Wafa, Matthias Engelmann, Jessica Ezri, Christian Felley, Markus Fliegner, Nicolas Fournier, Montserrat Fraga, Pascal Frei, Remus Frei, Michael Fried, Florian Froehlich, Christian Funk, Raoul Ivano Furlano, Suzanne Gallot-Lavallée, Martin Geyer, Marc Girardin, Delphine Golay, Tanja Grandinetti, Beat Gysi, Horst Haack, Johannes Haarer, Beat Helbling, Peter Hengstler, Denise Herzog, Cyrill Hess, Klaas Heyland, Thomas Hinterleitner, Philippe Hiroz, Claudia Hirschi, Petr Hruz, Rika Iwata, Res Jost, Pascal Juillerat, Vera Kessler Brondolo, Christina Knellwolf, Christoph Knoblauch, Henrik Köhler, Rebekka Koller, Claudia Krieger-Grübel, Gerd Kullak-Ublick, Patrizia Künzler, Markus Landolt, Rupprecht Lange, Frank Serge Lehmann, Andrew Macpherson, Philippe Maerten, Michel H Maillard, Christine Manser, Michael Manz, Urs Marbet, George Marx, Christoph Matter, Valérie McLin, Rémy Meier, Martina Mendanova, Christa Meyenberger, Pierre Michetti, Benjamin Misselwitz, Darius Moradpour, Bernhard Morell, Patrick Mosler, Christian Mottet, Christoph Müller, Pascal Müller, Beat Müllhaupt, Claudia Münger-Beyeler, Leilla Musso, Andreas Nagy, Michaela Neagu, Cristina Nichita, Jan Niess, Natacha Noël, Andreas Nydegger, Nicole Obialo, Carl Oneta, Cassandra Oropesa, Ueli Peter, Daniel Peternac, Laetitia Marie Petit, Franziska Piccoli-Gfeller, Julia Beatrice Pilz, Valérie Pittet, Nadia Raschle, Ronald Rentsch, Sophie Restellini, Jean-Pierre Richterich, Sylvia Rihs, Marc Alain Ritz, Jocelyn Roduit, Daniela Rogler, Gerhard Rogler, Jean-Benoît Rossel, Markus Sagmeister, Gaby Saner, Bernhard Sauter, Mikael Sawatzki, Michela Schäppi, Michael Scharl, Martin Schelling, Susanne Schibli, Hugo Schlauri, Sybille Schmid Uebelhart, Jean-François Schnegg, Alain Schoepfer, Frank Seibold, Mariam Seirafi, Gian-Marco Semadeni, David Semela, Arne Senning, Marc Sidler, Christiane Sokollik, Johannes Spalinger, Holger Spangenberger, Philippe Stadler, Michael Steuerwald, Alex Straumann, Bigna Straumann-Funk, Michael Sulz, Joël Thorens, Sarah Tiedemann, Radu Tutuian, Stephan Vavricka, Francesco Viani, Jürg Vögtlin, Roland Von Känel, Alain Vonlaufen, Dominique Vouillamoz, Rachel Vulliamy, Jürg Wermuth, Helene Werner, Paul Wiesel, Reiner Wiest, Tina Wylie, Jonas Zeitz, Dorothee Zimmermann
Inflammatory Bowel Diseases
Matiar Madanchi, Stefania Fagagnini, Nicolas Fournier, Luc Biedermann, Jonas Zeitz, Edouard Battegay, Lukas Zimmerli, Stephan R Vavricka, Gerhard Rogler, Michael Scharl, Claudia Anderegg, Peter Bauerfeind, Christoph Beglinger, Stefan Begré, Dominique Belli, José M Bengoa, Luc Biedermann, Beat Bigler, Janek Binek, Mirjam Blattmann, Stephan Boehm, Jan Borovicka, Christian P Braegger, Nora Brunner, Patrick Bühr, Bernard Burnand, Emanuel Burri, Sophie Buyse, Matthias Cremer, Dominique H Criblez, Philippe de Saussure, Lukas Degen, Joakim Delarive, Christopher Doerig, Barbara Dora, Gian Dorta, Mara Egger, Tobias Ehmann, Ali El-Wafa, Matthias Engelmann, Jessica Ezri, Christian Felley, Markus Fliegner, Nicolas Fournier, Montserrat Fraga, Pascal Frei, Remus Frei, Michael Fried, Florian Froehlich, Christian Funk, Raoul Ivano Furlano, Suzanne Gallot-Lavallée, Martin Geyer, Marc Girardin, Delphine Golay, Tanja Grandinetti, Beat Gysi, Horst Haack, Johannes Haarer, Beat Helbling, Peter Hengstler, Denise Herzog, Cyrill Hess, Klaas Heyland, Thomas Hinterleitner, Philippe Hiroz, Claudia Hirschi, Petr Hruz, Rika Iwata, Res Jost, Pascal Juillerat, Vera Kessler Brondolo, Christina Knellwolf, Christoph Knoblauch, Henrik Köhler, Rebekka Koller, Claudia Krieger-Grübel, Gerd Kullak-Ublick, Patrizia Künzler, Markus Landolt, Rupprecht Lange, Frank Serge Lehmann, Andrew Macpherson, Philippe Maerten, Michel H Maillard, Christine Manser, Michael Manz, Urs Marbet, George Marx, Christoph Matter, Valérie McLin, Rémy Meier, Martina Mendanova, Christa Meyenberger, Pierre Michetti, Benjamin Misselwitz, Darius Moradpour, Bernhard Morell, Patrick Mosler, Christian Mottet, Christoph Müller, Pascal Müller, Beat Müllhaupt, Claudia Münger-Beyeler, Leilla Musso, Andreas Nagy, Michaela Neagu, Cristina Nichita, Jan Niess, Natacha Noël, Andreas Nydegger, Nicole Obialo, Carl Oneta, Cassandra Oropesa, Ueli Peter, Daniel Peternac, Laetitia Marie Petit, Franziska Piccoli-Gfeller, Julia Beatrice Pilz, Valérie Pittet, Nadia Raschle, Ronald Rentsch, Sophie Restellini, Jean-Pierre Richterich, Sylvia Rihs, Marc Alain Ritz, Jocelyn Roduit, Daniela Rogler, Gerhard Rogler, Jean-Benoît Rossel, Markus Sagmeister, Gaby Saner, Bernhard Sauter, Mikael Sawatzki, Michela Schäppi, Michael Scharl, Martin Schelling, Susanne Schibli, Hugo Schlauri, Sybille Schmid Uebelhart, Jean-François Schnegg, Alain Schoepfer, Frank Seibold, Mariam Seirafi, Gian-Marco Semadeni, David Semela, Arne Senning, Marc Sidler, Christiane Sokollik, Johannes Spalinger, Holger Spangenberger, Philippe Stadler, Michael Steuerwald, Alex Straumann, Bigna Straumann-Funk, Michael Sulz, Joël Thorens, Sarah Tiedemann, Radu Tutuian, Stephan Vavricka, Francesco Viani, Jürg Vögtlin, Roland Von Känel, Alain Vonlaufen, Dominique Vouillamoz, Rachel Vulliamy, Jürg Wermuth, Helene Werner, Paul Wiesel, Reiner Wiest, Tina Wylie, Jonas Zeitz, Dorothee Zimmermann
Inflammatory Bowel Diseases
27.
Low serum folic acid can be a potential independent risk factor for erectile dysfunction: a prospective case–control study
Attia Abd Allah Attia, Mohamed Abd El Mawgood Amer, Mamdouh Hassan, Sameh Fayek GamalEl Din
International Urology and Nephrology
Attia Abd Allah Attia, Mohamed Abd El Mawgood Amer, Mamdouh Hassan, Sameh Fayek GamalEl Din
International Urology and Nephrology
28.
Interaction Effects of Plasma Vitamins A, E, D, B9, and B12 and Tobacco Exposure in Urothelial Bladder Cancer: A Multifactor Dimensionality Reduction Analysis
Fradj Ben, Dali Mrad, Amani Kallel, Mokhtar Bibi, Rhouma Ben, Haifa Sanhaji, Yassine Nouira, Moncef Feki
Nutrition and Cancer
Fradj Ben, Dali Mrad, Amani Kallel, Mokhtar Bibi, Rhouma Ben, Haifa Sanhaji, Yassine Nouira, Moncef Feki
Nutrition and Cancer
29.
Toxic elements in packed red blood cells from smoker donors: a risk for paediatric transfusion?
Renata Boehm, Carolina Cohen, Rianne Pulcinelli, Greice Caletti, Almeri Balsan, Sabrina Nascimento, Rafael Rocha, Enrique Calderon, Tatiana Saint’Pierre, Solange Garcia, Leo Sekine, Tor Onsten, Adriana Gioda, Rosane Gomez
Vox Sanguinis
Renata Boehm, Carolina Cohen, Rianne Pulcinelli, Greice Caletti, Almeri Balsan, Sabrina Nascimento, Rafael Rocha, Enrique Calderon, Tatiana Saint’Pierre, Solange Garcia, Leo Sekine, Tor Onsten, Adriana Gioda, Rosane Gomez
Vox Sanguinis
30.
High Serum Folate Concentration Is Associated with Better Lung Function in Male Chronic Obstructive Pulmonary Disease Patients Who Are Current Smokers: Analysis of Nationwide Population-Based Survey
Taeyun Kim, Chul-Ho Oak, Mann-Hong Jung, Tae-Won Jang, Jehun Kim
Nutrients
Taeyun Kim, Chul-Ho Oak, Mann-Hong Jung, Tae-Won Jang, Jehun Kim
Nutrients
31.
Novel predictive risk factor for Erectile Dysfunction: Serum folic acid
Abhimanyu Gupta, Shivam Priyadarshi, Nachiket Vyas, Govind Sharma, Prafulla Swain
Andrologia
Abhimanyu Gupta, Shivam Priyadarshi, Nachiket Vyas, Govind Sharma, Prafulla Swain
Andrologia
32.
Dietary Intake of Folate and Assessment of the Folate Deficiency Prevalence in Slovenia Using Serum Biomarkers
Igor Pravst, Živa Lavriša, Maša Hribar, Hristo Hristov, Naska Kvarantan, Barbara Seljak, Matej Gregorič, Urška Blaznik, Nadan Gregorič, Katja Zaletel, Adrijana Oblak, Joško Osredkar, Katja Žmitek, Anita Kušar
Nutrients
Igor Pravst, Živa Lavriša, Maša Hribar, Hristo Hristov, Naska Kvarantan, Barbara Seljak, Matej Gregorič, Urška Blaznik, Nadan Gregorič, Katja Zaletel, Adrijana Oblak, Joško Osredkar, Katja Žmitek, Anita Kušar
Nutrients
33.
Plasma Cotinine Is Positively Associated with Homocysteine in Smokers but Not in Users of Smokeless Tobacco
Elisabet Söderström, Torbjörn Nilsson, Jörn Schneede, Per-Magne Ueland, Øivind Midttun, Björn Gylling, Ingegerd Johansson, Johan Hultdin
International Journal of Environmental Research and Public Health
Elisabet Söderström, Torbjörn Nilsson, Jörn Schneede, Per-Magne Ueland, Øivind Midttun, Björn Gylling, Ingegerd Johansson, Johan Hultdin
International Journal of Environmental Research and Public Health
34.
A Retrospective Cross-Sectional Cohort Trial Assessing the Prevalence of MTHFR Polymorphisms and the Influence of Diet on Platinum Resistance in Ovarian Cancer Patients
Caitlin Phillips-Chavez, Jermaine Coward, Michael Watson, Janet Schloss
Cancers
Caitlin Phillips-Chavez, Jermaine Coward, Michael Watson, Janet Schloss
Cancers
35.
Interaction between serum vitamin C levels and smoking on the periodontal condition in older adults
Akihiro Yoshihara, Keisuke Nakashima, Kana Suwama, Ayuko Odajima, Takayuki Yamaga, Hiroshi Ogawa
Journal of Periodontal Research
Akihiro Yoshihara, Keisuke Nakashima, Kana Suwama, Ayuko Odajima, Takayuki Yamaga, Hiroshi Ogawa
Journal of Periodontal Research
36.
Epigenetic Determinants of Racial Disparity in Breast Cancer: Looking beyond Genetic Alterations
Shriya Joshi, Chakravarthy Garlapati, Ritu Aneja
Cancers
Shriya Joshi, Chakravarthy Garlapati, Ritu Aneja
Cancers
37.
Folate and vitamin B12 status: temporal evaluation after mandatory fortification in Brazil
Cecília Palchetti, Josiane Steluti, Cristiane Sales, Regina Fisberg, Dirce Marchioni
European Journal of Clinical Nutrition
Cecília Palchetti, Josiane Steluti, Cristiane Sales, Regina Fisberg, Dirce Marchioni
European Journal of Clinical Nutrition
38.
Association Between Serum Folate and Lung Function in People with and without Chronic Obstructive Pulmonary Disease: Results from NHANES 2007–2012.
Xiang wen, Huajing Yang, Luyao Wang
Xiang wen, Huajing Yang, Luyao Wang
39.
The dietary inflammatory index and new-onset hypertension in Chinese adults: a nationwide cohort study
Ze Xu, Xue Li, Li Ding, Zhaofeng Zhang, Yongye Sun
Food & Function
Ze Xu, Xue Li, Li Ding, Zhaofeng Zhang, Yongye Sun
Food & Function
40.
Folate Biomarkers, Folate Intake, and Risk of Death From All Causes, Cardiovascular Disease, and Cancer: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies
Melika Fallah, Maryam Karim Dehnavi, Keyhan Lotfi, Azadeh Aminianfar, Leila Azadbakht, Ahmad Esmaillzadeh
Nutrition Reviews
Melika Fallah, Maryam Karim Dehnavi, Keyhan Lotfi, Azadeh Aminianfar, Leila Azadbakht, Ahmad Esmaillzadeh
Nutrition Reviews
| eISSN: | 1617-9625 |
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